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目的:探讨宫颈癌患者的临床病理特征与影响预后效果的主要因素。方法:选择2011年3月~2012年3月间于我院接受治疗的宫颈癌患者100例,回顾性分析患者的临床资料,总结不同年龄患者的临床症状,腺癌与鳞癌患者的病理特征,探讨预后效果的影响因素。结果:年龄≤30岁的年轻患者与年龄>30岁的中老年患者相比,无症状情况较少,出血情况较多,差异明显,P<0.05;宫颈癌鳞癌与腺癌患者的脉管癌栓阳性率、淋巴管癌栓阳性率、肿瘤大小的比较无显著差异,P>0.05,不具有统计学意义;在淋巴癌是否转移、临床分期和肿瘤分型方面的比较有显著差异,P<0.05;随访结果显示,3年内共18例患者死亡,3年生存率为82.0%,死亡患者的生存期平均(18.5±2.3)个月;淋巴管癌栓、淋巴结是否转移、肿瘤大小对患者的预后效果无影响,临床分期、临床类型和治疗方案不同的患者预后效果有显著差异,P<0.05,差异显著,具有统计学意义。多因素分析结果显示,临床分期、临床类型和治疗方案为宫颈癌患者预后效果的独立影响因素。结论:影响宫颈癌患者预后效果的因素较多,临床上应当尽早确诊并给予手术联合放化疗等综合治疗,尤其是腺癌患者,加强护理中老年患者,避免其出血,延长生存时间,提高患者的生存率。
Objective: To investigate the clinicopathological features and prognostic factors of cervical cancer patients. Methods: A total of 100 cervical cancer patients treated in our hospital from March 2011 to March 2012 were retrospectively analyzed. The clinical data of patients with different ages were summarized. The pathological features of patients with adenocarcinoma and squamous cell carcinoma , To explore the impact of prognostic factors. Results: Young patients ≤30 years of age compared with the middle-aged and elderly patients> 30 years old, less asymptomatic, bleeding more, the difference was significant, P <0.05; squamous cell carcinoma of the cervix and adenocarcinoma patients with vascular The positive rate of thrombosis, the positive rate of thrombus in thrombus and the size of tumor did not differ significantly (P> 0.05), and there was no statistical significance. There were significant differences in lymph node metastasis, clinical stage and tumor type, P <0.05; The follow-up results showed that 18 patients died within 3 years, the 3-year survival rate was 82.0%, the average survival time of the patients died was (18.5 ± 2.3) months; lymphatic tumor thrombus and lymph node metastasis, The prognosis of patients with no effect, clinical stage, clinical type and treatment of patients with different prognosis were significantly different, P <0.05, significant difference, with statistical significance. Multivariate analysis showed that clinical staging, clinical types and treatment regimens were independent prognostic factors for cervical cancer patients. Conclusion: There are many factors affecting the prognosis of patients with cervical cancer, clinical diagnosis and surgery should be given as soon as possible combined with radiotherapy and chemotherapy and other comprehensive treatment, especially in patients with adenocarcinoma, care and treatment of elderly patients to avoid bleeding, prolong survival and improve patient The survival rate.