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利凡诺的含量测定63年版部颁标准124页用重量法。此法用的检品量多,而且测定费时,因此,用一种微量利凡诺的定量方法。经实验用重量法与亚硝酸钠比色法比较,认为亚硝酸钠比色法,操作简便,快速、检品用量少,重现性好,有实用意义,适用于基层医院制剂利凡诺注射液的含量控制,本文可供参考,现介绍如下: 一、基本原理利凡诺与亚硝酸钠在盐酸酸性条件下反应生成樱桃红色溶液,此樱桃红色,在一定条件下与其浓度成正比。
Determination of rivanol content The 63 edition of the ministerial standards page 124 by gravimetric method. This method used for seized more, and the determination of time-consuming, therefore, with a trace amount of rivanol quantitative method. Compared with the sodium nitrite colorimetric method by the experimental gravimetric method, sodium nitrite colorimetric method is considered, easy to operate, fast, less seized goods, good reproducibility, and has practical significance, suitable for primary hospital preparation rivanol Injection of content control, this article for reference, are as follows: First, the basic principle of Rivanol and sodium nitrite in hydrochloric acid under acidic conditions to produce cherry red solution, this cherry red, under certain conditions and its concentration is proportional to.