论文部分内容阅读
有实验显示体内铁浓度与心血管疾病的发生有相关性 ,但结果并不完全一致。也有证据表明锌有抗氧化和抗动脉粥样硬化作用。应用核显微镜技术 (核显微镜技术即联合运用扫描透射离子显微镜 ,卢瑟福反向散射光谱仪和质子诱导的 X线发射仪 )测量新近形成的动脉粥样硬化斑块中铁和锌的水平。结论为 :动脉粥样硬化早期损伤的形成可由增高的铁浓度形成的氧自由基积累造成 ,锌可拮抗这种作用 ,而更长时间的去铁治疗 ,有抗动脉粥样硬化作用。
Experiments have shown that iron concentrations in the body and the occurrence of cardiovascular disease are related, but the results are not exactly the same. There is also evidence that zinc has antioxidant and anti-atherosclerotic effects. Nuclear and microscopic techniques (nuclear microscopy using a combination of scanning transmission ion microscopy, Rutherford backscatter spectroscopy, and proton-induced X-ray emitters) were used to measure the levels of iron and zinc in newly formed atherosclerotic plaques. The conclusion is that the formation of early atherosclerotic lesions can be caused by the accumulation of oxygen free radicals formed by increased iron concentration, which is counteracted by zinc, whereas longer iron-lowering treatments have anti-atherogenic effects.