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曾有报道谓声门下狭窄的发生与胃酸反流入喉部有关,但未见有实验研究。Delahunty等已经证明在狗的声带突粘膜上间歇涂抹胃酸能引起声带肉芽肿,这种肉芽肿在组织学上和声门下狭窄的早期病变相似。本文报道一12岁女孩,因在9岁时头部外伤延及插管而引起声门下狭窄。在2年半期间虽经反复悬吊显微喉镜下行长效固类醇注射、激光切除、扩张术、自体肋软骨移植修复术,均无明显效果。在激光治疗过程中发现胃食管反流,高浓度酸性物质流入下咽和喉部,但患者无反流和吸入的症状,后来给予抗酸生活制度和口服H_2阻
It has been reported that the occurrence of subglottic stenosis and gastric acid reflux into the throat, but no experimental study. Delahunty et al. Have demonstrated intermittent application of gastric acid to the vaginal mucosal membranes of dogs can cause vocal cord granulomas that are histologically similar to early lesions of subglottic stenosis. This article reports a 12-year-old girl who causes subglotal stenosis due to prolonged intubation at the age of 9 years. In 2 and a half years after repeated suspension of microlaryngoscope descending long-acting solid alcohol injection, laser resection, dilation, autologous costal cartilage transplantation repair, no significant effect. During the laser treatment, gastroesophageal reflux was found, high concentrations of acidic substances flowed into the hypopharynx and larynx, but patients had no symptoms of reflux and inhalation. Later, they were given an antacid-living system and oral H 2 resistance