论文部分内容阅读
目的探讨评价应用无创机械通气对肺癌患者急性呼吸衰竭(呼衰)进行通气支持的意义和效果。方法我科2007年1月至2010年4月接受无创机械通气的肺癌患者急性呼吸衰竭病例26例,同期未行机械通气的30例急性呼吸衰竭肺癌患者设为对照组;无创机械通气以经面罩压力支持通气+呼气末正压通气(PSV+PEEP),上机前及上机后2h分别采动脉血气分析,用自身对照方法,采用t检验,比较无创机械通气前后呼吸频率动脉血气分析结果,并记录机械通气时间,最终结果,统计一周死亡率;对照组统计一周死亡率。结果无创机械通气后PaO2显著升高,氧合指数改善(P<0.05,PaCO2虽有下降,但差异无统计学意义(P>0.05),7例成功撤机,19例死亡,最短上机时间7h,最长8d,一周死亡率76.92%。对照组一周死亡率100%(P<0.05。结论应用无创机械通气对肺癌急性呼衰患者进行呼吸支持,是一项有价值的措施,部分患者可获得生存延长。
Objective To evaluate the value and effectiveness of noninvasive mechanical ventilation on ventilatory support for patients with acute respiratory failure (respiratory failure) in patients with lung cancer. Methods A total of 26 patients with acute respiratory failure from non-invasive mechanical ventilation in our department from January 2007 to April 2010 were enrolled in this study. Thirty patients with lung cancer with acute respiratory failure who did not undergo mechanical ventilation during the same period were enrolled as control group. Non-invasive mechanical ventilation Pressure support ventilation + positive end-expiratory pressure (PSV + PEEP), arterial blood gas analysis before and 2 h after the operation, using the self-control method, using t test to compare the respiratory rate before and after non-invasive mechanical ventilation arterial blood gas analysis results , And record the mechanical ventilation time, the final result, the statistical weekly mortality; control group, the statistical one-week mortality. Results The PaO2 was significantly increased and the oxygenation index was improved after noninvasive mechanical ventilation (P <0.05, PaCO2 was decreased, but there was no significant difference between the two groups (P> 0.05). Seven patients wearable successfully, 19 died, 7h, the longest 8d, the one-week mortality rate was 76.92%, and the one-week mortality rate was 100% in the control group (P <0.05) .Conclusion The use of noninvasive mechanical ventilation for respiratory support in patients with acute respiratory failure of lung cancer is a valuable measure. Get survival extended.