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本文应用电生学方法观察了不同浓度的花椒浸液对蟾蜍离体神经干 A、C 两类纤维动作电位幅度和传导速度的影响。结果表明:花椒浸液对 A、C 两类纤维动作电位幅度和传导速度均有明显的抑制效应。而且随着花椒浸液浓度的增高,两类纤维动作电位幅度明显下降(P<0.01),动作电位消失时间明显缩短(P<0.01)。动作电位幅度和传导速度与花椒浸液作用时间呈显著负相关(r=-0.901～-0.977,P<0.01)。在同一时间内给予花椒浸液,C 类纤维动作电位先被阻断,然后 A 类纤维动作电位被阻断。两类纤维动作电位均消失后,用标准Ringer 液(任氏液)浸泡均可再现。
In this paper, the effects of different concentrations of Zanthoxylum bungeanum on the amplitude and conduction velocity of action potentials of A and C fibers in isolated trunk of Toad were observed by using electrobiological method. The results showed that the extract of Zanthoxylum bungeanum had a significant inhibitory effect on the amplitude and conduction velocity of A and C fibers. Moreover, with the increase of the concentration of Zanthoxylum bungeanum, the amplitude of action potentials of both fibers decreased significantly (P <0.01), and the disappearance of action potential was significantly shorter (P <0.01). There was a significant negative correlation between the action potential amplitude and the conduction velocity and the action time of Zanthoxylum bungeanum (r = -0.901-0.977, P <0.01). At the same time to give pepper immersion, C-class action potential was first blocked, and then A-class action potential is blocked. After the disappearance of the action potentials of both types of fibers, the standard Ringer solution (Ringer’s solution) can be soaked.