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单克隆抗体已问世近20年,现有抗癌单抗的特性限制了它的应用。本文以抗膀胱癌单抗为例讨论制备更理想抗癌单抗的可行性方法、应用过程中如何弥补不足和基因工程抗体的一般概念。
Monoclonal antibodies have been around for nearly 20 years and the characteristics of the current anti-cancer monoclonal antibodies have limited their use. In this paper, anti-bladder cancer monoclonal antibody as an example to discuss the feasibility of preparing more ideal anti-cancer monoclonal antibody, how to make up for the lack of application process and the general concept of genetically engineered antibodies.