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慢性肾功能不全常伴有不同程度的继发性甲旁亢(SHPT),活性D3和钙剂的补充通常为治疗的重要手段[1],可是大剂量口服或静脉冲击给予1,25(OH)2D3治疗常导致高钙血症的发生。而且一些患者腺体结节性增生可能对活性D3产生抵抗,通常需要外科手术切除增生
Chronic renal insufficiency is often accompanied by varying degrees of secondary hyperparathyroidism (SHPT). Replenishment of active D3 and calcium is often an important treatment [1], but high-dose oral or intravenous shocks give 1,25 (OH 2D3 treatment often leads to the occurrence of hypercalcaemia. And some patients with glandular nodular hyperplasia may be resistant to active D3, usually require surgical removal of hyperplasia