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目的观察持续静脉点滴小剂量肾上腺素治疗小儿腹型过敏性紫癜的疗效。方法患者随机分两组,对照组:按常规治疗,避免过敏性食物和药物,激素采用地塞米松,初始用量为0.5mg/(kg.d)静脉点滴,同时辅以甲氰咪胍和扑尔敏治疗;治疗组:在常规治疗基础上,加用肾上腺素0.5mg加入0.9%氯化钠注射液500ml中以12～16滴/min持续静脉给药,2～3d后腹痛减轻、消失,肾上腺素停药。结果治疗组患者腹痛症状明显减轻且腹痛消失快,与对照组差异有统计学意义,P<0.05。结论持续静点小剂量肾上腺素配合激素治疗小儿腹型过敏性紫癜效果肯定,安全不良反应小。
Objective To observe the effect of continuous intravenous drip and small dose of epinephrine on infantile abdominal hyperretinal purpura. Methods Patients were randomly divided into two groups. The control group was treated with conventional therapy to avoid allergic foods and drugs. The dexamethasone was used as the hormone. The initial dose was 0.5 mg / (kg.d) intravenous drip. At the same time, In the treatment group, on the basis of routine treatment, the rats were treated with epinephrine 0.5mg plus 0.9% sodium chloride injection 500ml for 12-16 drops / min for continuous intravenous administration, abdominal pain was relieved and disappeared after 2 ~ 3d, Adrenaline withdrawal. Results In the treatment group, the symptom of abdominal pain was relieved and the abdominal pain disappeared rapidly. There was a significant difference between the two groups (P <0.05). Conclusion Persistent low-dose intravenous injection of epinephrine with hormone treatment of children with abdominal hypersensitivity purpura positive effect, the safety of adverse reactions.