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目的探讨子宫非典型性息肉样腺肌瘤(APA)。方法收集和观察6例子宫非典型性息肉样腺肌瘤的临床病理特点,并复习文献。结果 6例患者年龄33~53岁,平均43.5岁。主诉月经量增多、阴道异常出血,B超检查偶然发现。肿瘤最大径2~5 cm,平均2.6 cm。3例位于子宫体部,1例位于子宫下段,2例位于子宫底部。肿瘤形态主要表现为复杂的分支腺管状结构,4例见鳞化,2例见腺腔内红染颗粒样坏死物。1例癌变为高分化子宫内膜样腺癌。随访时间1~36个月,未见复发。结论子宫内膜非典型性息肉样腺肌瘤多数临床经过良好,少数APA进展为子宫内膜样腺癌。
Objective To investigate atypical polypus-like adenomyoma (APA) in uterus. Methods The clinical and pathological features of atypical polyp adenoidoma in 6 cases of uterus were collected and observed, and the literature was reviewed. Results Six patients were 33 to 53 years old with an average of 43.5 years old. Chief complaint increased menstrual flow, abnormal vaginal bleeding, B-test found by chance. The largest tumor diameter 2 ~ 5 cm, an average of 2.6 cm. Three were located in the uterus, one in the lower uterine segment and two in the uterus. Tumor morphology mainly manifested as complex branching glandular tubular structure, 4 cases of scaling, 2 cases of glandular cavity glandular red staining granular necrosis. One case of cancer turned into highly differentiated endometrioid adenocarcinoma. Follow-up time of 1 to 36 months, no recurrence. Conclusions The majority of endometrial atypical polyp leiomyoma are well-established and few APA progresses to endometrioid adenocarcinoma.