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目的:探讨整块取肾法与分侧取肾法、高渗枸橼酸钠腺嘌呤肾保存液(HCA)与乳酸林格液(LAL)的优劣,研究缺血时间的长短对移植肾原发性无功能(PNF)发生率的影响。方法:将1141次采用无心跳供者供肾所做同种异体肾移植患者的临床资料作回顾性分析,按不同的取肾方法、不同的保存方法、不同的缺血时间分组别进行比较,观察其统计学上的差异。结果:(1)整块取肾的热缺血时间与分侧取肾法相似,但进行肾移植术时前者更容易;(2)LAL组的术后见尿时间为(25.48±6.53)min,HCA组为(15.63±10.00)min(P<0.01),术后肾功能恢复正常所需时间前者为(8.65±3.39)d,后者为(6.66±2.73)d(P<0.05),PNF的发生率分别为11.11%,2.14%(P<0.01);(3)HCA组中,当总缺血时间分别为≤10,20,30,40,50和>50h时,其PNF的发生率分别为0%,1.83%,1.23%,6.25%,5.88%和9.52%。结论:(1)整块取肾法优于分侧取肾法;(2)HCA对移植肾的保存效果好于LAL;(3)HCA组中,总缺血时间的延长将明显延缓肾移植术后见尿时间、肾功能的恢复?
OBJECTIVE: To investigate the advantages and disadvantages of the whole kidney-taking method and the side-to-side kidney method, the hypertonic sodium citrate adenine-preserving solution (HCA) and lactated Ringer’s solution (LAL) Effect of primary nonfunctioning (PNF) incidence. Methods: The clinical data of 1141 allograft recipients who had no heartbeat donor donor kidney were retrospectively analyzed. According to different methods of taking kidney, different preservation methods and different ischemic time groups, Observe the statistical differences. Results: (1) The warm ischemic time of the whole kidney was similar to that of the kidneys of the kidney, but the former was easier when the kidney was transplanted. (2) The urinary time of postoperative urinary LAL was (25.48 ± 6) .53) min in HCA group and (15.63 ± 10.00) min in HCA group (P <0.01), and the former was (8.65 ± 3.39) d (6.66 ± 2.73) d (P <0.05). The incidence of PNF was 11.11% and 2.14% respectively (P <0.01). (3) In HCA group, The incidences of PNF were 0%, 1.83%, 1.23%, 6.25%, 5.88% when the total ischemic time were ≤10, 20, 30, 40, And 9.52%. (2) The preservation effect of HCA on graft kidney is better than that of LAL; (3) In HCA group, the prolongation of total ischemia will delay renal transplantation Urine after surgery, renal function recovery?