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肺癌、乳腺癌等恶性肿瘤综合治疗后生存期延长,但是,中枢神经系统转移影响了预后。我们从1968年2月至1992年6月共收治脑转移瘤58例,进行临床分析并探讨其放射治疗对策。 临床资料 病例选择:全部为我院收治的脑转移患者进行放射治疗者。共58例,男性36例,女性22例;年龄最小29岁,最大80岁,平均年龄50.1岁。 原发肿瘤:肺癌52例,占全组89.7％,其它原发肿瘤6例,占10.3％。肺腺癌20例,占肺癌组38.5％,小细胞未分化癌17例,占肺癌组32.7％,肺鳞癌10例,占肺癌组19.2％,无病理肺癌5例,占肺癌组9.6％。乳腺癌5例,占全组例数8.6％,喉鳞癌1例。 诊断依据;脑CT扫描证实49例,同位素扫描证实4例,脑血管造影证实4例,脑B超检查证实1例。 脑转移瘤临床表现;脑瘤型(头痛、呕吐、视乳头水肿、颅内压高)34例,占58.6％,卒中型(类似脑血管疾病症状)22例,占37.9％,癫痫型(以癫痫为首发症状)2例。占3.4％。
The survival period of lung cancer, breast cancer and other malignant tumors is prolonged after comprehensive treatment. However, the central nervous system metastasis affects the prognosis. From February 1968 to June 1992, we treated 58 patients with brain metastases, performed clinical analysis and explored their radiotherapy strategies. Clinical data Case selection: All patients with brain metastases admitted to our hospital were treated with radiation therapy. A total of 58 cases, 36 males and 22 females; youngest 29 years old, maximum 80 years old, mean age 50.1 years old. Primary tumors: 52 cases of lung cancer, accounting for 89.7% of the entire group, and 6 cases of other primary tumors, accounting for 10.3%. 20 cases of lung adenocarcinoma, accounting for 38.5% of lung cancer group, 17 cases of small cell undifferentiated carcinoma, accounting for 32.7% of lung cancer group, 10 cases of lung squamous cell carcinoma, accounting for 19.2% of lung cancer group, no pathological lung cancer in 5 cases, accounting for 9.6% of lung cancer group. Five cases of breast cancer accounted for 8.6% of the total number of cases, laryngeal squamous cell carcinoma in 1 case. According to the diagnosis, 49 cases were confirmed by brain CT scan, 4 cases confirmed by isotope scan, 4 cases confirmed by cerebral angiography, and 1 case confirmed by brain B-ultrasound. The clinical manifestations of brain metastases; brain tumor type (headache, vomiting, papilledema, high intracranial pressure) 34 cases, accounting for 58.6%, stroke type (similar to cerebrovascular disease symptoms) in 22 cases, accounting for 37.9%, epilepsy type (to Epilepsy is the first symptom. 2 cases. Accounted for 3.4%.