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我诊所近3年来对10例年老体弱不能承受手术或难以手术切除的肛门直肠癌患者,以电化学治疗。10例中,男6例,女4例,年龄55~75岁。肿瘤位于齿状线以下者2例,齿状线上者8例,10例均能指诊肿瘤的全部位。肿块大的约10cm×6cm×3cm,小的3cm×2.5cm×1.5cm,腺癌8例,转移病灶者1例,息肉恶性癌变1例,磷状细胞癌1例。治疗:局麻后扩肛,充分暴露病灶区。用中国原子能科学研究院研制的电化学肿瘤治疗,将铂金电极针直接刺人肿瘤内由外向内或由下向上贯穿整个肿瘤。视瘤体大小,可插电极针3~6支,交错按插电极针未插入的针电极余端套绝缘塑料管端连接在正电极电源线上,周围电极针尾端连接在负电极的电源线上,然后通电治疗,视病人感受情况,调高电压至6~8V,电流50~80mA,治疗量500~800库伦,治疗过程中电极周围可见白色气泡。有啪啪响声为止,直至肿瘤组织坏死变黑,一次治疗时间约1~2h,较大的肿瘤可分次治疗。结果:本组经1~2次电化学治疗后,肿瘤完全消失者6例,另4例患者肿瘤明显缩小,治疗前,10例病人伴里急后重及粘液脓血便,经治疗后症状消失4例,好转5例,1例腹股沟淋巴结转移。经治疗后10例患者体重均有所增加,6个月后死于并发症3例,肝脏转移3例,存活2年者2例。
In the past 3 years, my clinic has treated 10 elderly patients with anorectal cancer who cannot withstand surgery or are difficult to remove. In 10 cases, there were 6 males and 4 females, aged 55-75 years old. The tumors were located in 2 cases below the dentate line and 8 cases in the dentate line. All 10 cases were able to diagnose the tumor. The masses were approximately 10cm x 6cm x 3cm, small 3cm x 2.5cm x 1.5cm, 8 cases of adenocarcinoma, 1 case of metastatic lesions, 1 case of malignant polyposis, 1 case of squamous cell carcinoma. Treatment: Anal expansion after local anesthesia, fully exposed lesion area. Using the electrochemical tumor treatment developed by the China Institute of Atomic Energy, the platinum electrode needle directly penetrates the tumor from outside to inside or from bottom to top through the entire tumor. According to the size of the tumor, three to six electrode needles can be inserted, staggered according to the inserted electrode needle, and the non-inserted needle electrode is connected to the positive electrode power line, and the end of the surrounding electrode pin is connected to the power supply of the negative electrode. Online, and then electrified treatment, depending on the patient’s feelings, increase the voltage to 6 ~ 8V, current 50 ~ 80mA, treatment volume 500 ~ 800 Coulomb, white bubbles around the electrode during treatment. There is a buzzing noise until the necrosis of the tumor tissue becomes dark, the time for a treatment is about 1~2h, and the larger tumour can be treated in divided times. RESULTS: After 1~2 times of electrochemical treatment in this group, 6 cases had completely disappeared tumors, and the tumors of the other 4 patients were significantly reduced. Before treatment, 10 cases were associated with urgency and weight, mucus, pus, and blood, and 4 cases disappeared after treatment. Five cases were improved and one case had inguinal lymph node metastasis. After treatment, the body weights of the 10 patients increased, 6 died after complications in 3 cases, liver metastases in 3 cases, 2 cases survived in 2 cases.