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本文报告9例血栓性血小板减少性紫癜(TTp)之疗效,其中8例用血浆清除术和抗血小板制剂联合治疗,1例(例9)单用抗血小板制剂。单采血浆术系采用连续流动式血细胞分离器,每次清除血浆1500~4400ml,然后输入大致相等数量的同型新鲜冰冻血浆,每天或隔天1次,共3~10次,历时4~30天。抗血小板制剂系用阿斯匹林每天0.6~2.4g 和潘生丁每天200~600mg。这些抗血小板制剂以后继续用于维持治疗。7例同时用了皮质激素,2例作了脾切除术。
This article reports the efficacy of 9 cases of thrombotic thrombocytopenic purpura (TTp), of which 8 cases were treated with plasma sclerotherapy and antiplatelet agents, and 1 case (Table 9) with antiplatelet agents alone. The apheresis system uses a continuous flow cytometer that removes 1500 to 4400 ml of plasma each time and then enters approximately the same amount of homogenous fresh frozen plasma either daily or once a day for 3 to 10 times for 4 to 30 days . Anti-platelet preparations with aspirin daily 0.6 ~ 2.4g and dipyridamole daily 200 ~ 600mg. These antiplatelet agents continue to be used to sustain treatment later. 7 cases also used corticosteroids, 2 cases for splenectomy.