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目的观察乌司他丁对失血性休克患者血流动力学及多器官的保护作用方法将36例失血性休克的患者随机分为A组18例和B组18例,均按失血性休克的常规治疗,A组同时加用乌司他丁1~2μ/kg 结果应用乌司他丁复苏后.患者的收缩压、舒张压、平均压、心率均可得到明显的改善(P<0.01);乌司他丁疗效评价的两因素方差分析,乌司他丁和复苏时间均可影响疗效(P<0.01),但乌司他丁的P值比时间的P值小,对疗效的影响更大,心、肺、肝、肾、肠组织的损伤明显减轻。结论乌司他丁能够改善失血性休克患者的血流动力学、对多个器官具有保护作用,能够有效的辅助治疗失血性休克。
Objective To observe the effects of ulinastatin on hemodynamics and multiple organ in hemorrhagic shock patients. Methods Thirty-six patients with hemorrhagic shock were randomly divided into group A (18 cases) and group B (18 cases) After treatment with ulinastatin 1 ~ 2μ / kg in group A, systolic blood pressure, diastolic blood pressure, mean pressure and heart rate were all significantly improved after Ulinastatin resuscitation (P <0.01) The two-factor analysis of variance, ulinastatin and recovery time both could affect the efficacy of stastin (P <0.01), but the P value of ulinastatin was smaller than that of time, which had a greater impact on the curative effect, Heart, lung, liver, kidney, intestinal damage significantly reduced. Conclusion Ulinastatin can improve hemodynamics in patients with hemorrhagic shock, protect multiple organs and effectively treat hemorrhagic shock.