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目的:回顾性分析儿童胰腺实性假乳头状瘤(solid pseudopapillary tumor,SPT)的临床特征及多层螺旋CT(multidetector computed tomography,MDCT)影像学表现,并与成人胰腺SPT进行对照研究。方法:收集2000年1月至2012年12月行MDCT检查且病理确诊为胰腺SPT的102例病人。分析胰腺SPT的症状和CT病变部位、大小、形态、包膜、钙化、内部组成、密度和强化模式。对上述结果进行统计学处理,采用x~2和t检验。结果:共收集患儿18例(≤18岁),成人84例(>18岁)。患儿,男3例,女15例,平均年龄(15.1±1.91)岁,腹痛不适(9/18,50%)为儿童胰腺SPT最主要的临床表现;儿童病变平均直径明显大于成年病人[(9.1±3.8)cm比(5.9+3.2)cm,P=0.000 3];除肿瘤大小外,儿童和成人胰腺SPT的临床和影像学特点均无统计学差异。结论:对于10岁以上的女性儿童,胰腺有较大占位并具有典型SPT的MDCT影像学表现时,应考虑SPT可能。
Objective: To retrospectively analyze the clinical features of solid pseudopapillary tumor (SPT) in children and the imaging findings of multidetector computed tomography (MDCT) in children. Methods: A total of 102 patients who underwent MDCT and pathologically diagnosed as pancreatic SPT from January 2000 to December 2012 were collected. Pancreatic SPT symptoms and CT lesion location, size, morphology, capsule, calcification, internal composition, density and enhanced mode. The above results were statistically processed, using x ~ 2 and t test. Results: Totally 18 children (≤18 years old) and 84 adults (> 18 years old) were collected. There were 3 males and 15 females, with an average age of 15.1 ± 1.91 years old and abdominal pain discomfort (9 / 18,50%), which were the most common clinical manifestations of children with pancreatic SPT. The average diameter of children with lesions was significantly larger than that of adult patients [ 9.1 ± 3.8 cm vs 5.9 + 3.2 cm, P = 0.000 3]. There were no significant differences in the clinical and imaging features of SPT in children and adults except for tumor size. CONCLUSIONS: SPT may be considered in women with age 10 years and older who have large masses of the pancreas with MDCT imaging of typical SPT.