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目的:比较针灸配合药物治疗与单纯药物治疗男性骨质疏松症患者的疗效差异。方法:将55例男性骨质疏松症患者随机分为针药组(观察组25例)和药物组(对照组30例)。观察组在口服阿仑磷酸钠的基础上取脾俞、肾俞、命门、神阙等穴,采用针刺和温灸治疗;对照组单纯口服阿仑磷酸钠。两组均连续治疗6个月后观察临床症状积分和骨密度(BMD)的改善情况。结果:两组患者治疗后症状积分均明显降低(均P<0.001),观察组治疗后较对照组下降更明显(P<0.001);观察组腰椎和股骨BMD较治疗前明显提高(P<0.01,P<0.05),观察组治疗后腰椎BMD较对照组增加明显(P<0.05);对照组部分患者出现腹痛、腹泻、恶心、呕吐、消化不良等,观察组不良反应的程度及出现率较对照组明显减轻和降低。结论:针灸配合药物治疗男性骨质疏松症疗效较好、不良反应小,优于单纯口服阿仑磷酸钠。
Objective: To compare the curative effect of acupuncture and moxibustion with drug therapy and simple drug treatment in male patients with osteoporosis. Methods: 55 cases of osteoporosis were randomly divided into acupuncture group (25 cases in observation group) and drug group (30 cases in control group). Observation group oral alendronate on the basis of taking Pishu, Shenshu, life gate, Shen Que and other points, using acupuncture and warm moxibustion treatment; control group simply oral alendronate. Both groups were treated for 6 months after treatment to observe the improvement of clinical symptom score and bone mineral density (BMD). Results: After treatment, the symptom scores of both groups were significantly decreased (all P <0.001), and the observation group was more obvious than the control group after treatment (P <0.001); BMD of lumbar and femur in the observation group was significantly higher than that before treatment (P <0.01) , P <0.05). The BMD of the lumbar spine in the observation group increased significantly compared with that in the control group (P <0.05). Some patients in the control group had abdominal pain, diarrhea, nausea, vomiting and indigestion. The degree and incidence of adverse reactions in the observation group The control group significantly reduced and reduced. CONCLUSION: Acupuncture and Moxibustion combined with drugs have a better curative effect on osteoporosis in men and a lower adverse reaction than oral alendronate alone.