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目的:研究分析卵巢恶性肿瘤及子宫内膜异位(EM)病例,探讨两者在临床上的相互关系与诊治分析。方法:从2007年2月到2014年3月在我院治疗的原发性恶性卵巢肿瘤患者中选取220例病例,通过病理检测,将伴有子宫内膜异位的24例患者分为观察组,将不存在子宫内膜异位的196例病例分为对照组,对两组患者的疾病病例分期与肿瘤组织分类的临床资料进行分析比较。结果:原发恶性卵巢肿瘤并子宫内膜异位患者共24例,占10.91%,该组24例病例中,临床分期为Ⅰ期的病例共17例,占70.83%,不存在子宫内膜异位的对照组临床分期则以Ⅲ期占多数,共120例,占61.22%;通过组织学类型分析,观察组中内膜样癌病例为12例,透明细胞癌共6例,粘液性3例,浆液性2例,其它1例,其中透明细胞癌的子宫内膜异位发病率最高(p<0.05)。结论:经研究表明卵巢恶性肿瘤并子宫内膜异位的病例中以Ⅰ期病例最多,内膜异位恶变诊断可能与临床分期及组织病灶程度有关,尤其与透明细胞癌及内膜样癌的关系最为密切,由此推测内膜异位恶变可能是诱发这两类卵巢癌的因素之一。
Objective: To study the cases of malignant ovarian tumor and endometriosis (EM) and to explore their clinical correlation and diagnosis and treatment. Methods: From February 2007 to March 2014, 220 patients with primary malignant ovarian tumors treated in our hospital were selected. Twenty-four patients with endometriosis were divided into observation group , 196 cases without endometriosis were divided into control group, and the clinical data of the two groups were compared with the clinical data of tumor tissue classification. Results: Twenty-four patients (10.91%) had primary malignant ovarian tumor with endometriosis. Of the 24 patients in this group, there were 17 cases (70.83%) with stage Ⅰ clinical stage and no endometriosis The clinical stage of the control group was the majority of stage Ⅲ, a total of 120 cases, accounting for 61.22%; by histological type analysis, the observation group, 12 cases of endometrioid carcinoma, 6 cases of clear cell carcinoma, mucinous in 3 cases , Serous in 2 cases and the other 1 case, of which clear cell carcinoma had the highest incidence of endometriosis (p <0.05). Conclusion: The study shows that ovarian cancer and endometriosis in cases of stage Ⅰ cases, diagnosis of endometriosis may be related to clinical stage and the degree of tissue lesions, especially with clear cell carcinoma and endometrial carcinoma The most closely related to infer that malignant endometriosis may be induced by these two types of ovarian cancer one of the factors.