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丁香醚提物和水提物都能对抗乙酸提高小鼠腹腔毛细血管通透性,抑制二甲苯性小鼠耳壳肿胀和角叉莱胶性大鼠足跖肿胀;丁香水提物的抗炎作用强于醚提物,两者也能减少乙酸引起的小鼠扭体反应次数和延长热痛反应潜伏期。醚提物能显著减少蓖麻油引起的小鼠腹泻次数,而水提物则能显著减少番泻叶引起的小鼠腹泻次数。结果提示丁香的抗炎作用可能是其“温经止痛”和“温中止泻”的共同机理。
Clove ether extracts and aqueous extracts can improve acetic acid resistance in mouse abdominal cavity, inhibit ear swelling in xylene mice and swelling of paws in carrageenan mice; anti-inflammatory effects of clove water extract The effect is stronger than that of ether extract, both of which can also reduce the number of writhing responses induced by acetic acid in mice and prolong the latency of thermal pain response. Ether extract can significantly reduce the number of mice diarrhea caused by castor oil, while water extract can significantly reduce the number of diarrhea caused by senna. The results suggest that the anti-inflammatory effect of cloves may be the common mechanism of its “warming and analgesic” and “warming diarrhea”.