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前列腺癌是中老年男性常见的恶性肿瘤,发病率位居发达国家男性恶性肿瘤之首。目前前列腺癌的发生、发展、转移、复发等机制仍不甚明确,本文从肿瘤干细胞理论的角度对前列腺癌的细胞起源、疾病进展、肿瘤转移、复发以及前列腺癌干细胞的分离鉴定作一综述。
Prostate cancer is a common malignancy in middle-aged and elderly men, with the highest prevalence among the male malignancies in developed countries. At present, the mechanism of the occurrence, development, metastasis and recurrence of prostate cancer is still unclear. This article reviewed the origin of cells, disease progression, tumor metastasis and recurrence of prostate cancer and the isolation and identification of prostate cancer stem cells from the perspective of tumor stem cell theory.