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[目的]比较分析99mTc-MIBI SPECT/CT同机融合显像、99mTc-MIBI SPECT与CT对口腔颌面部肿块的诊断价值。[方法]对68例临床拟诊断为口腔颌面部肿块的患者术前行CT、99mTc-MIBI SPECT显像及99mTc-MIBI SPECT/CT同机融合显像。以术后病理结果作为金标准,分别计算以上3种方法对口腔颌面部肿块的诊断效能并利用受试者工作特征曲线(ROC)评估诊断价值。[结果]99mTc-MIBI SPECT/CT、99mTc-MIBI SPECT及CT诊断口腔颌面部肿块的灵敏度、特异性、准确率分别为80.65%、81.08%、80.88%;54.84%、72.97%、64.71%;51.61%、75.68%、64.71%。99mTc-MIBI SPECT/CT同机融合显像诊断口腔颌面部肿块的灵敏度和准确率较单独99mTc-MIBI SPECT显像或单独CT均明显提高,差异有统计学意义(P均<0.05)。99mTcMIBI SPECT/CT显像、99mTc-MIBI SPECT显像及CT的ROC曲线下面积分别为0.867、0.681和0.666。[结论]99mTc-MIBI SPECT/CT同机融合显像诊断口腔颌面部肿块较单一显像有较高的诊断价值。
[Objective] To compare the diagnostic value of 99mTc-MIBI SPECT / CT imaging and 99mTc-MIBI SPECT in the diagnosis of oral and maxillofacial masses. [Method] Sixty-eight patients with clinically planned oral and maxillofacial masses underwent preoperative CT, 99mTc-MIBI SPECT imaging and 99mTc-MIBI SPECT / CT fusion imaging. The postoperative pathological results were taken as the gold standard to calculate the diagnostic efficacy of the above three methods on the oral and maxillofacial masses respectively and evaluate the diagnostic value by using the receiver operating characteristic curve (ROC). [Results] The sensitivity, specificity and accuracy of 99mTc-MIBI SPECT / CT, 99mTc-MIBI SPECT and CT were 80.65%, 81.08%, 80.88%, 54.84%, 72.97% and 64.71% respectively for diagnosis of oral and maxillofacial mass. 51.61%, 75.68%, 64.71%. The sensitivity and accuracy of 99mTc-MIBI SPECT / CT fusion imaging in the diagnosis of oral and maxillofacial masses were significantly higher than 99mTc-MIBI SPECT or CT alone (all P <0.05). The area under the ROC curve of 99mTcMIBI SPECT / CT imaging, 99mTc-MIBI SPECT imaging and CT were 0.867,0.681 and 0.666, respectively. [Conclusion] The diagnostic value of 99mTc-MIBI SPECT / CT fusion imaging in the diagnosis of oral and maxillofacial masses is higher than single imaging.