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采用ＰＣＲ技术，对５０例胎儿组织ＤＮＡ进行了Ｙ染色体特异的ＳＲＹ基因扩增。扩增片段长度为２５０ｂｐ。结果显示：３２例早孕绒毛ＤＮＡ中，有１７例扩增出特异性片段．１５例未扩增出特异性片段，有、无特异性片段比例为１．１３３：１，接近胎儿自然出生性别之比；１８例中孕引产胎盘ＤＮＡ中８例阳性，１０例阴性，与引产胎儿实际性别完全一致。因ＰＣＲ扩增胎儿ＳＲＹ基因特异性强、灵敏度高，可用于早期胎儿性别的产前诊断。
Y chromosome-specific SRY gene amplification was performed on 50 fetal DNA using PCR. The amplified fragment length is 250bp. The results show that: 32 cases of early pregnancy villi DNA, 17 cases amplified specific fragments. 15 cases did not amplify specific fragments, there is no specific fragment ratio of 1.133: 1, close to the natural proportion of the fetus sex ratio; 18 cases of second trimester placenta DNA in 8 cases positive, 10 negative, and induced labor The actual sex of the fetus exactly the same. Due to PCR amplification of fetal SRY gene-specific, high sensitivity, can be used for prenatal diagnosis of fetal sex.