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双甲脒(Amitraz)是防治果树、棉花和水稻等作物害虫的甲脒类农药,其生物活性近似杀虫脒。本文主要对其有关毒理学研究结果进行介绍,以资为安全生产和使用双甲脒提供依据。 急性毒性 当给试验动物经口注入双甲脒后,动物出现活动减少、运动失调,一般在24—72小时死亡。双甲脒对大鼠和家兔的局部皮肤和眼粘膜没有刺激性。对哺乳动物的口服半数致死量以小鼠为例360,440(mg/kg)属于中等毒性的农药。
Amitraz is a carboxamidine pesticide against crop pests such as fruit trees, cotton and rice, and its biological activity is similar to that of chlordimeform. This article mainly introduces the results of its toxicology research, in order to provide the basis for the safe production and use of amitraz. Acute Toxicity When animals receive oral amitraz, animals appear to have reduced activity and exercise disorders, usually 24-72 hours of death. Amitraz is not irritating to the topical skin and mucous membranes of rats and rabbits. Oral LD50 to mammals in mice Example 360,440 (mg / kg) It is a moderately toxic pesticide.