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目的 分析帕金森病 (PD)大鼠肠神经系统(ENS)内在神经元的改变对胃动力的影响及其关系。方法 本实验依据帕金森病 (PD)的病理特点 ,用 6 羟多巴胺损毁大鼠单侧黑质 纹状体系统的多巴胺能神经元 ,通过行为检测 ,建立PD大鼠模型。并分别给予正常大鼠和模型鼠以左旋多巴 (Levo
Objective To analyze the effect of changes of intrinsic neurons in enteric nervous system (ENS) of rats with Parkinson’s disease (PD) on gastric motility and their relationship. Methods According to the pathological features of Parkinson’s disease (PD), we used 6-hydroxydopamine to destroy the dopaminergic neurons in the unilateral nigrostriatal system in rats. PD rats were established by behavioral testing. And were given normal rats and model mice levodopa (Levo