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研究品系和年龄增长对大鼠操作行为的影响。方法对ＳＤ和Ｗｉｓｔａｒ两种近交系大鼠三个年龄段（４、１０、１９月龄）时，于电脑控制的Ｓｋｉｎｎｅｒ测定箱中，采用正性强化物，进行了操作行为测定。将夜间进行的１５小时测定分为３０分钟活动和６０分钟非活动期，只有在活动期才可得到食物强化，并安排了高频度差别强化率（ＤＲＨ）和低频度差别强化率（ＤＲＬ）两个不同程序。每个程度按不断提高的学习要求又分为三个连续性阶梯：ＤＲＨ２／１、ＤＲＨ４／２、ＤＲＨ８／４及ＤＲＬ１／８、ＤＲＬ１／８、ＤＲＬ１／１６、ＤＲＨ１／３２。并对程度ＤＲＨ８／４和ＤＲＬ１／３２各进行了连续六天的获得性学习测定。对相同对象在６个月和９个月的间隔后进行了重复测定。结果在ＤＲＨ程序，随着年龄的增长，两品系鼠学习成绩都提高（Ｐ＜０．０５），品系差异不明显。然而在ＤＲＬ程度，成绩随年龄增长改变不大，Ｗｉｓｔａｒ鼠的成绩却始终比同年龄段ＳＤ鼠好（Ｐ＜０．０５）；遗憾的是ＳＤ鼠于第三次实验前大部分死亡而结果缺如。对明暗分辨学习成绩及ＤＲＨ８／４和ＤＲＬ１／３２两个程序获得性学习的分析亦呈现相同趋势。结论提示两品系大鼠都能很快学会简单程序，而且在较长间隔后对之仍有较?
The effect of strain and age on the behavior of rats was studied. Methods The behavioral behaviors of SD and Wistar inbred rats were evaluated in a computer-controlled Skinner box at three ages (4, 10, and 19 months of age) using positive potentiators. Night-time 15-hour measurements were divided into 30-minute activity and 60-minute inactivity, and food fortification was obtained only during the activity period. High-frequency differential strengthening rate (DRH) and low frequency differential strengthening rate (DRL) Two different programs. Each level is subdivided into three continuous steps according to increasing learning requirements: DRH2 / 1, DRH4 / 2, DRH8 / 4 and DRL1 / 8, DRL1 / 8, DRL1 / 16 and DRH1 / 32. And acquired six consecutive learning acquisitions for each of the levels DRH8 / 4 and DRL1 / 32. Repeated determinations of the same subjects were made after intervals of 6 months and 9 months. Results In the DRH program, both of the two strains improved their learning achievement (P <0.05) with age, but the difference was insignificant. However, at the level of DRL, scores did not change much with age. Wistar rats consistently performed better than SD rats of the same age group (P <0.05). Unfortunately, most of the SD rats died before the third experiment Missing. The same trend is also seen in the analysis of light-dark resolution learning and acquired learning of DRH8 / 4 and DRL1 / 32. Conclusions suggest that both strains of rats can quickly learn simple procedures, but after a longer interval is still more?