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目的:探讨中国中老年人群髋部骨折的疾病负担及其影响因素。方法:基于2015年中国健康与养老追踪调查数据，以伤残损失健康生命年（years lived with disability，YLD）率评价中国中老年人群髋部骨折的疾病负担，并分析性别、年龄（45~49岁、50~59岁、60~69岁和≥70岁）、文化程度（未受过教育、小学、初中、高中及以上）、地区（城市、农村）、人均国内生产总值（低、中和高）以及地理区域（北部地区、东部地区、中南地区、西北地区和西南地区）与髋部骨折YLD率的相关性。结果:排除基本信息、髋部骨折数据缺失者，共纳入研究对象17 830名，男8 405名，女9 425名；年龄（61.6±9.8）岁（范围45~105岁），男性（61.9±9.6）岁、女性（61.2±10.1）岁。髋部骨折总体患病率为2.3%（410/17 830）。YLD率为694/10万（95%不确定区间：462/10万，989/10万），其中男性组为693/10万（95%不确定区间：461/10万，988/10万）、女性组为696/10万（95%不确定区间：463/10万，992/10万），无性别差异。随年龄增长YLD率逐渐升高，70岁及以上人群达到1 155/10万（95%不确定区间：769/10万，1 646/10万）。随文化程度升高YLD率逐渐降低，文化程度为高中及以上人群YLD率低至434/10万（95%不确定区间：289/10万，619/10万）。农村地区YLD率为721/10万（95%不确定区间：480/10万，1 027/10万），高于城市地区的650/10万（95%不确定区间：433/10万，926/10万）。人均国内生产总值较高地区的YLD率为545/10万（95%不确定区间：363/10万，777/10万），低于人均国内生产总值较低地区的761/10万（95%不确定区间：506/10万，1 084/10万）。YLD率相对最高的地理区域为西北地区[1 056/10万（95%不确定区间：703/10万，1 506/10万）]，其次为西南地区[887/10万（95%不确定区间：590/10万，1 264/10万）]，最低为东北地区[317/10万（95%不确定区间：211/10万，452/10万）]。结论:髋部骨折给中国中老年人群造成了沉重的疾病负担，且不同地理区域差异明显。高龄、农村地区、文化程度较低和人均国内生产总值较低是我国髋部骨折疾病负担的影响因素。“,”Objective:To estimate the burden of hip fractures and related factors among the Chinese middle-aged and elderly population.Methods:Based on the data of China Health and Retirement Longitudinal Study (CHARLS) in 2015, the burden of hip fractures among Chinese middle-aged and elderly population was evaluated as the years lived with disability (YLD) rate. The relationship between gender, age (45-49, 50-59, 60-69 and ≥70 years old), educational level (no education, elementary school, junior high school, high school and above), region (urban, rural), gross domestic production (GDP) per capita (low, medium and high) and geographic area (northern, eastern, south-central, northwest and southwest regions) and the YLD rate of hip fractures were analyzed, respectively.Results:Excluding items with missing basic information and hip fracture data, a total of 17,830 subjects (8,405 males and 9,425 females) were included in the study with average age 61.6±9.8 years (range 45 to 105 years). The average age in male was 61.9±9.6 years, and that in female was 61.2±10.1 years. The prevalence of hip fractures was 2.3% (410/17,830). The total YLD rate was [694/100,000 (95% Uncertainty Interval (n UI): 462/100,000, 989/100,000)]. The YLD rates were similar between male [693/100,000 (95%n UI: 461/100,000, 988/100,000)] and female [696/100,000 (95%n UI: 463/100,000, 992/100,000)] subgroups. The YLD rate of hip fractures was increasing with age, which reached at maximum of 1,155/100,000 (95%n UI: 769/100,000, 1,646/100,000) for participants aged 70 years or above. The rate was gradually decreased with the upgrade of the educational level. The participants with high school education and above reached the lowest of 434/100,000 (95%n UI: 289/100,000, 619/100,000). In addition, the YLD rate of hip fractures in rural areas [721/100,000 (95%n UI: 480/100,000, 1,027/100,000)] was higher than that in urban areas [650/100,000 (95%n UI: 433/100,000, 926/100,000)]. The YLD rate in areas with higher GDP per capita [545/100,000 (95%n UI: 363/100,000, 777/100,000)] was lower than that in areas with lower GDP per capita [761/100,000 (95%n UI: 506/100,000, 1,084/100,000)]. Moreover, the participants living in the Northwest region were with the highest YLD rate of hip fractures [1,056/100,000 (95%n UI: 703/100,000, 1,506/100,000)], followed by the Southwest region [887/100,000 (95%n UI: 590/ 100,000, 1,264/100,000)] and the Northeast region [317/100,000 (95%n UI: 211/100,000, 452/100,000)].n Conclusion:Hip fractures exerted heavy burdens on the Chinese middle-aged and elderly population. The YLD rate of hip fractures varied according to geographical regions, greater age, rural areas, low educational levels and low GDP per capita. These related factors could affect the disease burden of hip fractures in China.