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目的:观察米库氯铵与瑞芬太尼在小儿扁桃腺样体摘除术中应用的临床效果,并进行分析讨论。方法:收集本院2012年01月至2013年06月耳鼻喉科行扁桃腺样体摘除术的患儿64例,并将其随机分为两组,其中对照组( S组)行以往七氟醚、维库溴铵和芬太尼全麻手术比较两组两种方法在小儿扁桃体腺样体摘除术中的临床效果观察,观察组(M组)行米库氯铵与瑞芬太尼,丙泊酚维持全麻组。结果:两组患儿的术后SBP、DBP、HR、SPO2各参数比较,S组均较M组为高,但均无显著性差异(P﹥0.05),两组患儿停药后呼吸恢复时间及清醒时间M组均少于S组,两组比较有显著性差异(P<0.05)。结论:米库氯铵与瑞芬太尼及丙泊酚等短效静脉麻醉药物,在小儿扁桃体腺样体摘除术中无气道刺激性,麻醉效果确切,术后烦躁发生率较低,安全可行,临床上值得推广。“,”ObjectiveTo investigate the feasibility of mivacurium and remifentanil and the effects on postoperative recovery and conscious state in children undergoing tonsillectomy.MethodsSixty-four ASA physical statusⅠandⅡ patients undergoing elective tonsillectomy surgery were included.Patients were randomly divided into two group:group M and group S (n=32): group S patients received general anesthesia with sevouflurane,vecuronium and fentanyl intravenously. The group M patients received general anesthesia with propofol, mivacurium and remifentanil intravenously.ResultsThere was no significant difference in SBP,DBP,HR and SPO2 during the general anesthesia between the two groups.Recovery time of respiratory and waking in group M were significantly earlier than those in group S (P<0.05).ConclusionsMivacurium and remifentanil can be applied safely in children undergoing tonsillectomy.