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This paper proposes a scheme of parameter perturbation to suppress the stable rotating spiral wave, meandering spiral wave and turbulence in the excitable media, which is described by the modified Fitzhugh-Nagumo (MFHN) model. The controllable parameter in the MFHN model is perturbed with a weak pulse and the pulse period is decided by the rotating period of the spiral wave approximatively. It is confirmed that the spiral wave and spiral turbulence can be suppressed greatly. Drift and instability of spiral wave can be observed in the numerical simulation tests before the whole media become homogeneous finally.