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目的探讨营养支持对老年结直肠癌患者手术治疗效果的影响。方法将90例老年结直肠癌患者分为肠内营养支持组(试验组)和常规治疗组(对照组),每组均为45例,进行临床对比分析。结果围手术期无死亡,对照组并发症发生率为17.8%明显高于试验组4.4%(P<0.05)。试验组和对照组胃肠功能恢复时间、平均住院时间分别为(41.42±10.82)h vs(62.43±14.45)h和(16.81±6.42)d vs(26.1±10.31)d,试验组较对照组明显缩短(P<0.05)。手术后试验组体重、血清蛋白回升较对照组明显提前,试验组由负氮平衡向正氮平衡恢复所需时间(7.74±1.29)d较对照组(11.36±2.41)d明显缩短(P<0.05)。结论老年结直肠癌患者围手术期营养支持的理想方法是肠外营养加肠内营养,有利于改善患者的营养状况,提高对手术创伤的耐受性,降低并发症的发生率。
Objective To investigate the effect of nutritional support on the surgical treatment of elderly patients with colorectal cancer. Methods 90 elderly patients with colorectal cancer were divided into enteral nutrition support group (experimental group) and conventional treatment group (control group), 45 cases in each group, clinical comparative analysis. Results There were no perioperative deaths. The incidence of complications in the control group was 17.8%, significantly higher than that in the experimental group (4.4%, P <0.05). The recovery time of gastrointestinal function and average length of hospital stay in trial group and control group were (41.42 ± 10.82) h vs (62.43 ± 14.45) h and (16.81 ± 6.42) d vs (26.1 ± 10.31) d, respectively. Shortened (P <0.05). The body weight and serum protein level of the test group were significantly earlier than those of the control group after operation. The time required for the test group to recover from the negative nitrogen balance to the positive nitrogen balance (7.74 ± 1.29) d was significantly shorter than that of the control group (11.36 ± 2.41) d (P <0.05) ). Conclusion The ideal method of perioperative nutritional support for elderly patients with colorectal cancer is parenteral nutrition plus enteral nutrition, which is beneficial to improve the nutritional status of patients, improve the tolerance to surgical trauma and reduce the incidence of complications.