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垂体瘤转化基因 (PTTG)是新近发现的一种肿瘤转化基因 ,其在多种正常增生性组织中有表达 ,在多种恶性肿瘤组织中呈现高表达。通过体内、体外试验均证实PTTG在促进细胞转化及肿瘤形成中起着重要作用 ,并与部分肿瘤侵润和转移有关
Pituitary tumor transforming gene (PTTG) is a recently discovered tumor transforming gene that is expressed in various normal proliferative tissues and highly expressed in various malignant tumors. Through in vivo and in vitro experiments, it was confirmed that PTTG plays an important role in promoting cell transformation and tumor formation and is associated with invasion and metastasis of some tumors