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目的观察卡孕栓宫腔给药防治剖宫产术后出血的效果及安全性。方法将100例剖宫产产妇随机分成两组,治疗组(50例)于剖宫产中缝合子宫切口前放置1 mg卡孕栓于宫腔底部;对照组(50例)不放置卡孕栓。两组均于胎儿娩出后宫体注射缩宫素10 U。结果治疗组术中及术后2 h内出血量分别为(218±50)m、l(366±54)m l,对照组术中及术后2 h内出血量分别为(249±53)m、l(415±60)m l,两组比较差异均有统计学意义(P<0.01);治疗组用药前后血压变化差异无统计学意义(P>0.05),无一例不良反应发生。结论卡孕栓预防剖宫产术后出血效果好,安全,不良反应少,用药方法简单,值得推广。
Objective To observe the efficacy and safety of intrauterine administration of carbamazepine in prevention of bleeding after cesarean section. Methods 100 cases of cesarean section were randomly divided into two groups. The treatment group (50 cases) placed 1 mg of cardiopulmonary embolus in the bottom of uterine cavity before cesarean section in cesarean section. The control group (50 cases) . Both groups were injected with oxytocin 10 U after the fetus was delivered. Results The amount of bleeding in the treatment group was (218 ± 50) m and 1 (366 ± 54) ml respectively during operation and 2 hours after operation. The amount of bleeding in the control group was (249 ± 53) m, (415 ± 60) ml, there was significant difference between the two groups (P <0.01). There was no significant difference in blood pressure before and after treatment in the treatment group (P> 0.05). No adverse reaction occurred. Conclusion Carprost suppository prevention of bleeding after cesarean section is good, safe, less adverse reactions, the medication method is simple, it is worth promoting.