Determination and Correlation of 1-Octanol/Water Partition Coefficients for Six Quinolones from 293.

• 作 者: ZHANG Cong-liang WANG Yan
• 机 构: CollegeofChemicalEngineering
• 出 处: 高等学校化学研究：英文版
• 发表日期: 2010年4期
• 关键词: 喹诺酮类 分配系数 测定 关联 温度效应 氧氟沙星 诺氟沙星 洛美沙星 Quinolone 1-Octanol/water partition coeffic
• 基金项目: Supported by the Natural Science Foundation of Henan Province, China（No.0611033400）.

<正>A shake-flask method was used to determine 1-octanol/water partition coefficients of ofloxacin,norfloxacin, lomefloxacin,ciprofloxacin,pefloxacin and pipemidic acid from 293.15 K to 323.15 K.The results show that 1-octanol/water partition coeffic