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目的 探索脑型血吸虫病的临床特点。方法 选择2010年3月至2016年3月江西省寄生虫病防治研究所临床部治疗的14例脑型血吸虫病人的临床资料进行分析。结果 14例患者中12例诊断为慢性型,2例诊断为急性型,血清、脑脊液均为血吸虫抗体阳性。嗜酸性粒细胞增高者10例,百分比为5.1%~60.3%。Kato-Katz法粪检查见血吸虫卵7例。13例行内科治疗,12例治愈,1例好转;1例手术切除病灶。结论 脑型血吸虫病主要表现为癫痫、头痛、头昏、发热等。头颅MRI特征性影像呈簇状聚集融合成团块状。脑型血吸虫病口服吡喹酮治疗可以取得很好的预后。
Objective To explore the clinical features of cerebral schistosomiasis. Methods Clinical data of 14 cases of schistosomiasisis treated by clinical department of Institute of Parasitic Diseases in Jiangxi Province from March 2010 to March 2016 were analyzed. Results Of the 14 patients, 12 were diagnosed as chronic type, 2 were diagnosed as acute type, and the serum and cerebrospinal fluid were all positive for schistosome antibody. Eosinophilia in 10 cases, the percentage of 5.1% to 60.3%. Kato-Katz fecal examination found schistosome eggs in 7 cases. 13 cases were treated by internal medicine, 12 cases were cured, 1 case was improved; 1 case was treated by surgery. Conclusion Cerebral schistosomiasis is mainly manifested as epilepsy, headache, dizziness, fever and so on. The characteristic images of the cranial MRI were clustered and clustered into clumps. Cerebral schistosomiasis oral praziquantel treatment can achieve a good prognosis.