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通过近十几年来对心源性猝死的研究发现,神经系统在病因方面是一个重要因素。治疗上的进展,如β阻滞剂减少心肌梗塞病人猝死的可能性,使人们对神经系统与猝死的密切关联倍加注意。一、植物神经系统与Q-T间期延长 QT间期延长可导致致命性室性心律失常。已知的继发因素有药物如奎尼丁、双异丙吡胺、酚噻嗪类及三环类抗忧郁剂;电解质紊乱如低钾、低镁、低钙和缺血性心脏病等。自1975年首次发现家族性QT延长综合症、即原发性QT延长综合症(Jervell-
After nearly a decade of sudden cardiac death found that the nervous system in the etiology is an important factor. Therapeutic advances, such as the use of beta-blockers to reduce the risk of sudden death in patients with myocardial infarction, doubled the awareness of the close association between the nervous system and sudden death. First, the autonomic nervous system and Q-T interval prolongation QT interval can lead to life-threatening ventricular arrhythmias. Known secondary factors are drugs such as quinidine, diazepam, phenothiazines and tricyclic antidepressants; electrolyte disorders such as hypokalemia, low magnesium, low calcium and ischemic heart disease. First discovered in 1975, familial QT prolongation syndrome, that is, the primary QT prolongation syndrome (Jervell-