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本文通过光镜和电镜观察了鹌鹑动脉粥样硬化时动脉形态的变化以及中药漏芦对其病变的影响。结果表明:鹌鹎食高脂45天后,动脉壁严重受损,内皮层不完整,内皮细胞及平滑肌细胞均表现为细胞器增多,平滑肌细胞增生,并见较多的泡沫细胞。而漏芦组无论从病变的发生率及病变的程度都比高脂组明显减轻。提示:漏芦能减轻高脂对动脉壁的损伤,减少脂质的堆积,因此能较好的保护动脉细胞超微结构的完整性。
In this paper, light and electron microscopy were used to observe the change of arterial shape in atherosclerosis of the popliteal artery and the effect of Rhizoma argenteum on its pathological changes. The results showed that after 45 days of high fat diet, the arterial wall was severely damaged and the endothelial layer was incomplete. The endothelial cells and smooth muscle cells showed increased organelles, smooth muscle cell proliferation, and more foam cells. The incidence of lesions and lesions in the Liaolu group was significantly reduced compared with the high-fat group. It is suggested that Legolite can reduce high-fat injury to the arterial wall and reduce the accumulation of lipids, so it can better protect the ultrastructure of arterial cells.