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目的:分析妊娠期高血压疾病患者凝血功能4项指标改变及检测的临床意义。方法:检测50例正常非孕妇、67例晚期妊娠妇女和70例妊娠期高血压疾病患者血浆凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)和纤维蛋白原(Fbg)水平,并进行统计学分析。结果:晚期妊娠妇女的PT、APTT、TT、Fbg与正常非孕妇比较差异有统计学意义,妊娠期高血压疾病患者的PT、APTT、Fbg、TT与晚期妊娠妇女、正常非孕妇比较差异有统计学意义(P<0.05)。结论:妊娠期高血压疾病患者存在明显的高凝状态,对妊娠期高血压疾病患者进行凝血功能指标检测,对妊娠期高血压疾病病情评估和预防D IC的发生有重要意义。
Objective: To analyze the changes of coagulation function in patients with gestational hypertension and the clinical significance of detection. Methods: The plasma prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT) and fibrin in 50 cases of normal non-pregnant women, 67 cases of late pregnant women and 70 cases of gestational hypertensive disorders were measured. (Fbg) levels, and statistical analysis. Results: The PT, APTT, TT, Fbg in late pregnant women were significantly different from those in normal non-pregnant women. The differences of PT, APTT, Fbg, TT in pregnant women with hypertensive disorder complicating pregnancy and normal pregnant women were statistically significant Significance (P <0.05). Conclusion: There is a significant hypercoagulable state in patients with hypertensive disorder complicating pregnancy. The detection of coagulation parameters in patients with hypertensive disorder complicating pregnancy is of great significance in assessing the condition of hypertensive disorders in pregnancy and preventing the occurrence of D IC.