论文部分内容阅读
目的观察体外循环术中、术后严格血糖控制对非糖尿病患者体外循环术后高敏C反应蛋白的影响。方法 64例患者随机分为两组,A组作为强化治疗组从手术开始即行强化胰岛素治疗,将血糖严格控制于3.9～8.3 mmol/L。B组作为对照组将血糖控制在11.1 mmol/L以下。体外循环术后检测血液高敏C反应蛋白浓度。结果两组病例的一般情况比较差异无统计学意义。A组高敏C反应蛋白浓度较B组明显降低,差异有统计学意义(P<0.05)。结论体外循环术中、术后应用胰岛素严格控制血糖可降低患者高敏C反应蛋白水平,减轻炎症反应。
Objective To observe the effect of postoperative strict glycemic control on high-sensitivity C-reactive protein after cardiopulmonary bypass in non-diabetic patients undergoing cardiopulmonary bypass. Methods Sixty-four patients were randomly divided into two groups. Group A, as the intensive treatment group, received intensive insulin therapy from the beginning of surgery. The blood glucose was controlled strictly at 3.9 to 8.3 mmol / L. Group B as a control group to control blood sugar below 11.1 mmol / L. Cardiopulmonary bypass after blood high-sensitivity C-reactive protein concentration. Results There was no significant difference in the general situation between the two groups. The concentration of high-sensitivity C-reactive protein in group A was significantly lower than that in group B, the difference was statistically significant (P <0.05). Conclusions During cardiopulmonary bypass, strict control of blood glucose after insulin therapy can reduce high-sensitivity C-reactive protein and alleviate inflammation.