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目的:观察中西医结合治疗绝经后骨质疏松症的临床疗效。方法:将120例患者随机分为2组各60例,对照组采用西药治疗,治疗组在对照组治疗的基础上加用中药治疗。观察治疗前后临床疗效、腰椎骨密度(BM D)、血清钙(Ca)及血清碱性磷酸酶(ALP)的变化情况。结果:临床疗效总有效率治疗组为88.3%,对照组为61.7%,2组比较,差异有非常显著性意义(P<0.01)。提示治疗组疗效优于对照组。治疗后2组腰椎BM D均较治疗前显著增加,差异有显著性或非常显著性意义(P<0.05,P<0.01)。治疗后2组比较,治疗组改善腰椎BM D均优于对照组,差异有显著性意义(P<0.05)。治疗后2组血Ca、ALP较治疗前均有明显改善,差异有显著性或非常显著性意义(P<0.05,P<0.01)。治疗后2组比较,治疗组改善血Ca、ALP疗效优于对照组,差异均有显著性意义(P<0.05)。结论:中西医结合治疗绝经后骨质疏松症疗效确切,安全性好,有较高的临床应用价值。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of postmenopausal osteoporosis. Methods: 120 patients were randomly divided into two groups of 60 cases, the control group treated with western medicine, the treatment group in the control group based on the treatment with traditional Chinese medicine. The clinical effects, BMD, Ca and ALP were observed before and after treatment. Results: The total effective rate of the treatment group was 88.3% in the control group and 61.7% in the control group. There was significant difference between the two groups (P <0.01). Prompt treatment group than the control group. After treatment, BMD of lumbar vertebrae in two groups increased significantly compared with that before treatment, the difference was significant or very significant (P <0.05, P <0.01). After treatment, the improvement of lumbar BMD in the treatment group was better than that in the control group, the difference was significant (P <0.05). After treatment, blood Ca and ALP in two groups were significantly improved compared with before treatment, the difference was significant or very significant (P <0.05, P <0.01). Compared with the control group, the treatment group improved the efficacy of blood Ca and ALP, the difference was significant (P <0.05). Conclusion: The combination of TCM and Western medicine for the treatment of postmenopausal osteoporosis is effective, safe, and has high clinical value.