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应用经颅多普勒超声(TCD)技术,观察36例普通型和典型偏头痛患者实施星状神经节阻滞(SGB)治疗前后大脑中动脉和颞浅动脉血流速度(υmca,vsta)的变化。结果发现,实施SGB前,36例患者的υmca和υsta较正常为高(P<0.05)。行SGB后,31例(86.1%)患者υmca和υsta下降接近正常,头痛消失或症状缓解;5例(13.9%)患者的颅内和颅外血流速度变化差异不显著(P>0.05),头痛症状无明显改善。提示偏头痛患者发作期的大脑中动脉和颞浅动脉主干处于轻度痉挛状态。多数患者对SGB和神经调节反应敏感,受累血管可能处于功能性轻度狭窄;而少数患者对SGB和神经调节反应较差,可能系该血管已有器质性改变或有其它潜在的致病因素。
Transcranial Doppler ultrasound (TCD) was used to observe the changes of blood flow velocity (υmca, vsta) of middle cerebral artery and superficial temporal artery before and after stellate ganglion block (SGB) in 36 patients with common and typical migraineurs Variety. The results showed that υmca and υsta of 36 patients were higher than normal before the implementation of SGB (P <0.05). After SGB, 31 cases (86.1%) had similar decrease in υmca and υsta, with disappearance of headache or symptom relief. There was no significant difference in intracranial and extracranial blood flow velocity in 5 cases (13.9%) (P > 0.05), no significant improvement in headache symptoms. Tip migraine patients in the attack of the middle cerebral artery and superficial temporal artery in a mild spasticity. Most patients are susceptible to SGB and neuromodulation, and implicated vessels may be functional mild stenosis; while a minority of patients respond poorly to SGB and neuromodulation, possibly due to organic changes in the blood vessel or other underlying risk factors .