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目的:评价足踝调衡法结合中药熏洗治疗急性踝关节扭伤的临床疗效。方法:将符合入选标准的2018年1月－2021年1月本院62例急性踝关节扭伤患者采用随机数字表法分为2组，每组31例。对照组给予足踝调衡法治疗，观察组在对照组基础上结合中药熏洗。2组均治疗7 d。采用VAS量表，Kofoed踝关节功能评分量表，美国矫形外科足踝协会评分系统（American Orthopaedic Foot and Ankle Association Ankle Hindfoot Scale，AOFAS）评估患者踝关节疼痛程度及踝足功能恢复情况；采用ELISA法检测血浆P物质、神经肽、神经生长因子（nerve growth factor，NGF）、IL-1β、IL-6、hs-CRP水平，评价临床疗效。结果:观察组总有效率为96.8%（30/31）、对照组为77.4%（24/31），2组比较差异有统计学意义（n χ2=5.17，n P=0.023）。治疗后1、3、7 d，观察组VAS评分均低于对照组（n t值分别为4.86、5.19、3.86，n P<0.01），Kofoed评分均高于对照组（n t值分别为2.03、2.58、2.46，n P<0.05），AOFAS疼痛评分均高于对照组（n t值分别为2.61、2.47、4.90，n P<0.05）。治疗后，观察组P物质［（2.94±0.91）mg/L比（3.69±0.94）mg/L，n t=3.19］、神经肽［（141.06±16.31）ng/L比（165.22±17.63）ng/L，n t=3.16］、NGF［（43.65±10.15）ng/L比（52.26±10.20）ng/L，n t=3.33］水平均低于对照组（n P<0.01），IL-1β、IL-6、hs-CRP水平均低于对照组（n t值分别为2.60、2.64、2.42，n P<0.05）。n 结论:足踝调衡法推拿联合中药熏洗可快速缓解急性踝关节扭伤患者的疼痛程度，恢复关节功能，提高疗效。“,”Objective:To explore the clinical curative effect of foot-ankle balance massage combined with herbal fumigation on acute ankle sprain.Methods:According to random number table method, 62 patients with acute ankle sprain meeting the inclusion criteria in the hospital were divided into control group and observation group between January 2018 and January 2021, 31 in each group. The control group was treated with foot-ankle balance massage, while the observation group added herbal fumigation treatment on the basis of the control group treatment. Both were treated for 7 days. The pain degree was evaluated by Visual Analogue Scale (VAS). The pain sites of ankle joint were evaluated by Kofoed ankle scale. The recovery of ankle and foot function was evaluated by American Orthopaedic Foot and Ankle Society (AOFAS). The levels of plasma substance P, neuropeptide, nerve growth factor (NGF), IL-1β, IL-6 and hs-CRP were detected by enzyme-linked immunosorbent assay. The clinical curative effect was assessed.Results:The differences in total response rate between observation group and control group were statistically significant [96.8% (30/31) n vs. 77.4% (24/31)] (n χn 2=5.17, n P=0.023). At 1st day, 3rd day and 7th day after treatment, VAS scores in observation group were significantly lower than those in the control group (n t=4.86, 5.19, 3.86, n P<0.01), Kofoed scores were significantly higher than those in the control group (n t=2.03, 2.58, 2.46, n P<0.05), and AOFAS pain scores were significantly higher than those in the control group (n t=2.61, 2.47, 4.90, n P<0.05). After treatment, levels of substance P [(2.94±0.91) mg/Ln vs. (3.69±0.94) mg/L, n t=3.19], neuropeptide [(141.06±16.31) ng/L n vs. (165.22±17.63) ng/L, n t=3.16] and NGF [(43.65±10.15) ng/L n vs. (52.26±10.20) ng/L,n t=3.33] in observation group were significantly lower than those in the control group (n P<0.01), and levels of IL-1β, IL-6 and hs-CRP were significantly lower than those in the control group (n t=2.60, 2.64, 2.42, n P<0.05).n Conclusion:The foot-ankle balance massage combined with herbal fumigation can quickly relieve pain, increase levels of pain substances, reduce levels of inflammatory cytokines and improve curative effect in patients with acute ankle sprains.