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Aim: To observe the efficacy and safety of quinacrine sterilization.Methods: This retrospective study was to evaluate the efficacy and safetyof quinacrine sterilization in 572 cases in Jiangsu and Guizhou Provincesfrom 1993 to 1997. A total of 588 cases of surgical sterilization performed atthe same time served as the controls. Results: Two groups had similardemographic and gynecological characteristics. The multiple decrement lifetable analysis showed that the 12th month gross cumulative failure rate forquinacrine sterilization was 3.13% . Serious side effects occurred in 2 cases(0.35%); one is ectopic pregnancy (20 months after treatment) and theother, allergy reaction (10 minutes after the second insertion). The liverand renal functions were all normal in both groups. No cance cells/suspect-ed cancer cells were found. In the quinacrine group, the acceptability was99.6% . Conclusions: The quinacrine method has a high acceptability,but the efficacy is relatively low. It is a safe method of contraceptio
Aim: To observe the efficacy and safety of quinacrine sterilization. Methods: This retrospective study was to evaluate the efficacy and safety of quinacrine sterilization in 572 cases in Jiangsu and Guizhou Provinces from 1993 to 1997. A total of 588 cases of surgical sterilization performed on att same time The multiple decrement lifetable analysis showed that the 12th month gross cumulative failure rate for quinacrine sterilization was 3.13%. Serious side effects occurred in 2 cases (0.35%); one is ectopic pregnancy (20 months after treatment) and theother, allergy reaction (10 minutes after the second insertion). The liverand renal functions were all normal in both groups. No cance cells / suspect-ed cancer cells were found. In the quinacrine group, the acceptability was99.6%. Conclusions: The quinacrine method has a high acceptability, but the efficacy is relatively low. It is a safe meth od of contraceptio