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目的:探讨酚妥拉明联合小剂量多巴胺在新生儿坏死性小肠结肠炎治疗中的临床价值。方法:选取我院收治的94例新生儿坏死性小肠结肠炎患儿进行研究,采用随机数字表法将患儿分为两组,对照组47例,采用酚妥拉明静滴治疗,观察组47例,采用酚妥拉明与小剂量多巴胺联合治疗,对比两组效果。结果:观察组患儿平均禁食时间、平均住院时间均明显短于对照组(p<0.05);观察组患儿手术率及不良反应发生率均明显小于对照组(p<0.05)。结论:采用酚妥拉明联合小剂量多巴胺方式对新生儿坏死性小肠结肠炎患儿实施治疗可显著缩短患者禁食时间及住院时间,并且有利于减少不良反应发生,降低手术率,临床价值显著,值得推广应用。
Objective: To investigate the clinical value of phentolamine combined with low-dose dopamine in the treatment of neonatal necrotizing enterocolitis. Methods: 94 cases of neonatal necrotizing enterocolitis treated in our hospital were selected for study. The children were divided into two groups by random number table method. In the control group, 47 cases were treated with intravenous infusion of phentolamine. The observation group Forty-seven patients were treated with phentolamine in combination with low-dose dopamine to compare the effects of the two groups. Results: The average fasting time and average length of hospital stay in the observation group were significantly shorter than those in the control group (p <0.05). The operative rate and incidence of adverse reactions in the observation group were significantly lower than those in the control group (p <0.05). Conclusion: The treatment of neonatal neonatal necrotizing enterocolitis with phentolamine combined with low-dose dopamine can shorten the fasting time and hospitalization time significantly, and is beneficial to reduce the incidence of adverse reactions and reduce the operation rate, the clinical value is significant , It is worth promoting application.