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我们曾报道针刺镇痛过程中家兔和大鼠纹状体及下丘脑以及家兔脑脊液脑啡肽含量增加。本文则研究吗啡镇痛过程中家兔脑及脑脊液甲硫-脑啡肽含量的变化,并和针刺比较。方法痛阈测定、针刺及脑啡肽含量的放射免疫测定等方法同前文。选择兔耳钾离子透入法痛阈在1.5毫安以下的家兔埋植慢性侧脑室套管。动物用戊巴比妥钠30毫克/公斤静脉注射
We have reported increased levels of enkephalin in rabbit and rat striatum and hypothalamus, and in rabbit cerebrospinal fluid during acupuncture analgesia. This article is to study morphine analgesia rabbit brain and cerebrospinal fluid methylthio-enkephalin changes, and compared with acupuncture. Methods Pain threshold determination, acupuncture and enkephalin content by radioimmunoassay and other methods with the previous. Rabbit ear potassium iontophoresis method selected pain threshold below 1.5 mA in rabbits implantation of chronic lateral cannulation. Animals were injected intravenously with pentobarbital sodium 30 mg / kg