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目的:观察纳洛酮联合醒脑静在急性酒精中毒治疗中的疗效。方法:选取我院于2014年6月至2016年6月收治的132例确诊为急性酒精中毒的患者,将其随机分为对照组和观察组。对照组给予纳洛酮治疗,观察组在对照组的基础上加用醒脑静治疗。观察两组的治疗效果。结果:观察组意识恢复清醒时间、中毒症状消失时间、肢体运动恢复时间均明显短于对照组,观察组平均动脉压显著高于对照组(P<0.05)。观察组的治疗总有效率明显高于对照组(97.0%vs 66.7%,P<0.05)。结论:纳洛酮联合醒脑静治疗急性酒精中毒具有协同作用,明显缩短意识恢复清醒时间、中毒症状消失时间、肢体运动恢复时间,值得临床大力推广。
Objective: To observe the efficacy of naloxone and xingnaojing in the treatment of acute alcoholism. Methods: A total of 132 patients diagnosed as acute alcoholism admitted from June 2014 to June 2016 in our hospital were selected and randomly divided into control group and observation group. The control group was treated with naloxone. The observation group was treated with xingnaojing on the basis of the control group. Observed the treatment effect of two groups. Results: The awake time of consciousness recovery, the disappearance of poisoning symptoms and limb movement recovery time in the observation group were significantly shorter than those in the control group. The mean arterial pressure in the observation group was significantly higher than that in the control group (P <0.05). The total effective rate of observation group was significantly higher than that of control group (97.0% vs 66.7%, P <0.05). Conclusion: Naloxone combined with xingnaojing has a synergistic effect on the treatment of acute alcoholism, significantly shortening the recovery time of consciousness, the disappearance of poisoning symptoms and the recovery time of limb movement, which is worth promoting in clinic.