【摘 要】
:
Filled with more than 60 different types of hydrolases,the acidic organelle lysosome governs cellular digestion by removing damaged organelles and catabolic products(Xu and Ren,2015).
【机 构】
:
Division of Pharmacology,Department of Neuroscience,Reproductive and Odontostomatological Sciences,S
论文部分内容阅读
Filled with more than 60 different types of hydrolases,the acidic organelle lysosome governs cellular digestion by removing damaged organelles and catabolic products(Xu and Ren,2015).
其他文献
Spinal cord injury (SCI), second only to stroke, is the leading cause of paralysis. The ability to walk is often lost after SCI, reducing independence and quality of life. Restoration of walking is cited as a priority among persons with SCI of all degrees
Peripheral nerve injuries are common consequences of extremity trauma or chronic compression with a prevalence of 43.8 per 1 million people (on average) reported in the United States annually, accompanied by a yearly increase in cost of care. Patients suf
Parkinson\'s disease (PD) is the second most common neurodegenerative disease affecting 8–10 million people worldwide. Moreover, PD is the fastest-growing neurodegenerative disease and it is predicted that the number of patients will double in the next
Exposure to noise of high intensities (> 80 dB) is considered a stressful event and might produce both auditory and extra-auditory damage, including different central nervous system (CNS) injuries. Within the CNS, the hippocampus (HC), a structure related
Trace amines are the class of endogenous biogenic amines that traditionally include beta-phenylethylamine,p-tyramine,tryptamine,octopamine,and others.
Ischemic stroke is a cerebrovascular disease with a high risk of mortality and long-lasting neurological disabilities. Medical advances have resulted in a declining trend in stroke incidence and deaths in the United States. However, increasing age and ris
The preservation of cognitive longevity and arresting the pandemic of senile dementia engulfing the modern world is arguably the major challenge faced by biomedical research in the 21st century. Age is the leading risk factor for neurodegenerative disease
The approval of oral disease modifying therapies (DMTs) for relapsing-remitting multiple sclerosis (RRMS) has changed considerably the therapeutic scenario and they often represent the first therapeutic choice for patients with RRMS, since their safety an
The formation and preservation of long-term memories critically depend upon coordinated activity of neuronal circuits, intracellular signaling cascades and synaptic remodeling (Josselyn et al., 2015). These essential processes occur in specific cell popul
The amyloid hypothesis of Alzhemer\'s disease (AD) postulates that the generation of amyloid-beta (Aβ) peptide from the amyloid precursor protein (APP) by the action of the γ-secretase complex is one of the principal causes of AD. This idea is supported