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目的探讨硝普钠联合厄贝沙坦对顽固性心衰的治疗效果。方法对65例顽固性心衰患者静脉滴注硝普钠,口服厄贝沙坦,并于治疗前、后行心脏彩超、胸部正位片检查,同时测量血压、心率、观察肺部啰音、水肿变化。结果与治疗前比较,治疗后左室舒张末径(LDV)、心输出量(CO)增多,左室射血分数(EF)增加,心胸比例缩小、血压、心率、肺部啰音、水肿明显改善(P<0.01)。治疗后临床总有效率为92.3%。结论硝普钠联合厄贝沙坦治疗顽固性心衰疗效显著。
Objective To investigate the therapeutic effect of sodium nitroprusside and irbesartan on refractory heart failure. Methods 65 patients with intractable heart failure intravenous infusion of sodium nitroprusside, irbesartan, and before and after treatment of cardiac echocardiography, chest anteroposterior examination, while measuring blood pressure, heart rate, pulmonary rales were observed, Edema changes. Results Compared with before treatment, left ventricular diastolic diameter (LDV), cardiac output (CO) increased, left ventricular ejection fraction (EF) increased, cardiothoracic proportion decreased, blood pressure, heart rate, pulmonary rales and edema were obvious Improve (P <0.01). After treatment, the total clinical effective rate was 92.3%. Conclusion Sodium nitroprusside combined with irbesartan treatment of refractory heart failure significant effect.