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由于EB病毒基因组可在多数鼻咽癌癌组织中被发现,而且许多鼻咽癌患者的血清中EB病毒的抗体(IgA)呈阳性,因此目前认为EB病毒感染与鼻咽癌的发病有一定的关系。BHRF1为一种早期表达蛋白,在所有野生型EB病毒的裂解液中均可被检测到。其序列高度保守,因而猜
Because Epstein-Barr virus genomes are found in most nasopharyngeal carcinoma tissues and many Epstein-Barr virus antibodies (IgA) in the serum of patients with nasopharyngeal carcinoma are positive, EB virus infection is currently believed to be associated with the pathogenesis of NPC relationship. BHRF1 is an early expression protein that can be detected in all wild type EB virus lysates. Its sequence is highly conserved, so guess