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随着幽门螺杆菌(Hp)对甲硝唑耐药性的流行,促进了对其它有效的抗Hp药物的研究.喹诺酮类药物在体外抗Hp显示相当低的MIC,但是在体内酸性环境中活性较弱.我们建议用质子泵抑制剂来提高这类药物的功效.
Studies of other potent anti-Hp drugs are promoted as the prevalence of metronidazole resistance by Helicobacter pylori (Hp) quinolones show a rather low MIC in vitro against Hp, but in vivo in an acidic environment Weaker We recommend using proton pump inhibitors to increase the potency of these drugs.