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植物内生真菌的代谢产物中存在一系列具有多样性结构的抗植物病原真菌的活性化合物(AFC)。本文以化合物结构为线索,对植物内生真菌所产生的具有抗植物病原真菌活性的生物碱、肽类、萜类、甾体、醌、有机酸、酯类等化合物的结构,对病原菌的抑制效果及其寄主植物等几方面进行了总结。从3个方面简单介绍了农用抗生素的作用机制,即作用于真菌细胞壁、细胞膜,以及抑制真菌蛋白质的生物合成。最后对AFC作为新型农用抗生素来源的前景进行了展望,其具有作为先导化合物,开发高效、低毒、无公害农用抗生素的巨大潜力。
There is a series of active compounds (AFCs) against phytopathogenic fungi with diverse structures in the metabolites of plant endophytic fungi. In this paper, the structure of compounds as a clue, the plant endophyte fungi have anti-plant pathogenic fungi alkaloids, peptides, terpenes, steroids, quinones, organic acids, esters and other compounds structure, inhibition of pathogens Effects and host plants, etc. were summarized. The mechanism of action of agricultural antibiotics is briefly introduced from three aspects, that is, acting on fungal cell walls, cell membranes, and inhibiting the biosynthesis of fungal proteins. Finally, the prospect of AFC as a new source of agricultural antibiotics is prospected. It has great potential as a leading compound to develop high efficiency, low toxicity and pollution-free agricultural antibiotics.