论文部分内容阅读
为了解T1DM治疗研究的进展概况。通过英特网检索T1DM治疗研究相关的文献,得知目前采用胰岛移植治疗T1DM的临床应用成功的病例较多,但存在着供体胰岛量严重不足和移植物排斥反应,严重制约着胰岛移植的发展,因此提出治疗T1DM的根本出路在于干细胞移植,而干细胞移植的主要障碍为自身免疫系统的攻击和培养干细胞的最佳条件的选择。多数研究还在实验室和动物实验阶段,特别是对能分泌胰岛素细胞的分离、纯化、培养、增殖等尚处于探讨之中。可见T1DM的治疗研究近年来已取得很大进展,彻底根治T1DM的出路在于胰岛干细胞移植。
To understand the progress of T1DM treatment research. Through the Internet to search the literature about T1DM treatment research, we know that the successful clinical application of islet transplantation in the treatment of T1DM is more successful, but there is a serious shortage of donor islets and graft rejection, seriously restricting islet transplantation Therefore, the fundamental way out for the treatment of T1DM is stem cell transplantation, and the main obstacle for stem cell transplantation is the selection of the best conditions for attack of the immune system and the cultivation of stem cells. Most studies are still in the laboratory and animal experiments stage, especially for the secretion of insulin cells separation, purification, culture, proliferation are still under discussion. Visible T1DM treatment research has made great progress in recent years, radical cure for T1DM is the islet stem cell transplantation.